Read the following article and Answer the questions below.
http://www.hhmi.org/news/goldstein2.html
1. Who was the Howard Hughes Medical Institute investigator?
2. What University did he work at?
3. He showed that "disruption of the transport system caused by defects in these proteins can lead to ___________________________".
4. What is the name of the peptide found in the brains of Alzheimer patients?
5. APP serves as an attachment point for a molecular motor called what?
6. Nerve cells have the unique property of what?
7. What are the 2 other key Alzheimer's disease related proteins discovered?
8. If APP is missing, normal cell cargo transport is ________________.
9. What portion of APP is where the motor molecule kinesin attaches?
10. If the enzyme breaks off the C-terminus, what happens to the kinesin?
11. Who is more susceptible to developing Alzheimer's disease?
1.)Lawrence Goldstein
ReplyDelete2.)University in Califoria, San Diego
3.)Nerve cell death
4.)Amyloid-beta
5.)Kinesin
6.)Sending out tendrils, called axons, up to several feet from the main cell body to innervate distant parts of the body.
7.)Beta-secretase and presenilin-1, are found together with APP inside the packet
8.)Somehow disrupted in Alzheimer’s disease, according to Goldstein.
9.)C-terminus
10.)Liberated and the transport process is disrupted
11.)People who suffer trauma to the brain
1. Lawrence Goldstein
ReplyDelete2. University of CA in San Diego
3. Death of nerve cells
4. Amyloid-beta peptide
5. Kinesin molecular model
6. Have unique property of sending out tendrils (axons) up to several feet from the main cell body to innervate distant parts of the body.
7. Beta-secratase and presenilin-1
8. Stalled
9. C-terminus
10. Kinesis is liberated
11. People who suffer trauma to the brain
Lindsay Plampin
ReplyDelete1. Lawrence Goldstein
2. University of California, in San Diego
3. Death of nerve cells
4. Amyloid-Beta
5. Kinesin
6. Sending tendrils (axons) up to several feet from the main cell body to innervate distant parts of the body
7. Beta-secratase and presenilin-1
8. Stalled
9. C-Terminus
10. Kinesis is liberated
11. People who suffer trauma to the brain
1)Lawrence Goldstein
ReplyDelete2)University of Califronia, San Diego
3)Nerve cell death
4) Amyloid-beta peptide
5) Kinesin molecular model
6)Sends out tendrils (axons) several feet from the main cell body to innervate distant parts of the body.
7)Beta-secratase and presenilin-1
8) Stalled
9)C-terminus
10) It is liberated
11)People who suffer trauma to the brain
1. Lawrence Goldstein
ReplyDelete2. University of California, San Diego
3. Nerve cell death
4. Amyloid-beta
5. Kinesin
6. Sending out tendrils called axons up to several feet from the main cell body to innervate distnat parts of the body.
7. Beta secretase and presenilin-1
8. Stalled
9. C- terminus
10. Kinesin is liberated
11. People who suffer trauma to the brain
1. Lawrence Goldstein
ReplyDelete2. University of CA in San Diego
3. Death of nerve cells
4. Amyloid-beta peptide
5. Kinesin molecular model
6. Have unique property of sending out tendrils (axons) up to several feet from the main cell body to innervate distant parts of the body.
7. Beta-secratase and presenilin-1
8. Stalled
9. C-terminus
10. Kinesis is liberated
11. People who suffer trauma to the brain
Hunter Rhyne
ReplyDelete1. Lawrence Goldstein
2. University of CA
3. Death of the nerve cell
4. Amyloid beta Peptide
5. Kinesin
6. Sending axons from the main cell body to innervate distant parts of the body.
7. Beta-secratase and presenilin-1
8. Stalled
9. C-terminus
10. Kinesis is liberated
11. Brain trauma patients
Darrielle Fair
ReplyDelete1.Lawrence Goldstein
2.University of California, San Diego
3.The death nerve cells
4.Amyloid-beta
5.Kinesin molecular model
6.they have a unique property of sending out tendrils, called axons, up to several feet from the main cell body to innervate distant parts of the body.
7.Beta-secretase and presenilin-1
8.Stalled
9.C- terminus
10.It is liberated and the transport process is disrupted.
11.People who suffer trauma to the brain.
Candice Bess
ReplyDelete1. Lawrence Goldstein
2. University of California, San Diego.
3. Nerve cell death
4. Amyloid-beta
5. Kinesin
6. sending out tendrils, called axons, up to several feet from the main cell body to innervate distant parts of the body.
7. beta-secretase and presenilin-1
8. Stalled
9. C-terminus
10. kinesin is liberated and the transport process is disrupted.
11. people who suffer trauma to the brain
Jayna Stachurski
ReplyDelete1. Lawrence Goldstein
2. Uni. of California at San Diego
3. the death of nerve cells.
4. Amyloid-Beta peptide.
5. Kinesin
6. Being able to send out long tendrils called axons from the main cell body to other parts in the body.
7. Presenilin-1 and beta-secretase
8. Stalled
9. C-terminus
10. Kinesin is liberated and the process gets interrupted.
11. People that suffer from brain trauma.
Codey Kirkpatrick
ReplyDelete1)Lawrence Goldstein
2)University of California, San Diego
3)death of nerve cells
4)Amyloid-Beta
5)Kinesin
6)the ability to send out long tendrils, axons, from the main cell to innervate distant parts of the body.
7)Beta-secretase, Presenilin-1
8)Stalled
9)C-Terminus
10)Kinesin is liberated
11)Persons who suffer from brain trauma
Jenna Pruitt
ReplyDelete1. Lawrence Goldstein
2. University of California,San Diego
3. Death of nerve cells
4. Amyloid-beta
5. Kinesin
6. Sends out tendrils (axons) several feet from the main cell body to innervate distant part of the body
7. Beta-secretase and presenilin-1
8. stalled
9. C-terminus
10. Kinesin is liberated
11. People who suffer trauma to the brain
ReplyDelete1.)Lawrence Goldstein
2.)University of California, San Diego
3,)Nerve cell death
4.)Amyloid-beta
5.)Kinesin
6.)Sending out tendrils(axons), up to several feet from the main cell body to innerrvate distant parts of the body
7.)Beta-secretase and presenilin-1
8.)Stalled
9.)C-terminus
10.)Kinesin is liberated and the transport process is disrupted
11.)People who suffer trauma to the brain
1. Lawrence Goldstein
ReplyDelete2. University of CA in San Diego
3. Death of nerve cells
4. Amyloid-beta peptide
5. Kinesin molecular model
6. Have unique property of sending out tendrils (axons) up to several feet from the main cell body to innervate distant parts of the body.
7. Beta-secratase and presenilin-1
8. Stalled
9. C-terminus
10. Kinesis is liberated
11. People who suffer trauma to the brain
This comment has been removed by the author.
ReplyDeleteSamantha Izaguirre
ReplyDelete1. Lawrence Goldstein
2. University of California, in San Diego
3. The nerve cells die
4. Amyloid-Beta
5. Kinesin
6. Sending tendrils (axons) up to several feet from the main cell body to innervate distant parts of the body
7. Beta-secratase and presenilin-1
8. Stalled
9. C-Terminus
10. Kinesis is liberated
11. People who suffer trauma to the brain
1. Lawrence Goldstein
ReplyDelete2. University of California, San Diego
3. the nerve cell dies
4. Amyloid-Beta
5. Kinesin
6. Sending out tendrils (axons) up to several feet from the main cell body to innervate distant parts of the body.
7. Beta-secratase and Presenilin-1
8. Stalled
9. C-Terminus
10. Kinesis is liberated and the process gets interrupted.
11. people who suffer brain trauma.